6SRH: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2117

PDB ID: 6SRHDownload
MMDB ID: 179699
PDB Deposition Date: 2019/9/5
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6SRH: monomeric; determined by author
Molecular Components in 6SRH
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
1
4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine
2
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
5
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303