6SMB: Human jak1 kinase domain in complex with inhibitor

PDB ID: 6SMBDownload
MMDB ID: 187043
PDB Deposition Date: 2019/8/21
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.04  Å
Source Organism:
Similar Structures:
Biological Unit for 6SMB: monomeric; determined by author
Molecular Components in 6SMB
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak1
(Gene symbol: JAK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{H}-indol-7-yl]-2-methyl-pyridine-3-carboxamide~{N}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{H}-indol-7-yl]-2-methyl-pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303