6SD9: Crystal structure of wild-type cMET bound by foretinib

PDB ID: 6SD9Download
MMDB ID: 178544
PDB Deposition Date: 2019/7/26
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 6SD9: monomeric; determined by author and by software (PISA)
Molecular Components in 6SD9
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideN-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303