6SBU: X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3)

PDB ID: 6SBUDownload
MMDB ID: 188736
PDB Deposition Date: 2019/7/22
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 2.91  Å
Source Organism:
Similar Structures:
Biological Unit for 6SBU: tetrameric; determined by author and by software (PISA)
Molecular Components in 6SBU
Label Count Molecule
Proteins (4 molecules)
4
L-lactate Dehydrogenase a Chain
(Gene symbol: LDHA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid
2
1
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303