6S9X: Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 15c

PDB ID: 6S9XDownload
MMDB ID: 180542
PDB Deposition Date: 2019/7/15
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6S9X: monomeric; determined by author and by software (PISA)
Molecular Components in 6S9X
Label Count Molecule
Protein (1 molecule)
1
Rac-alpha Serine/threonine-protein Kinase
(Gene symbol: AKT1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{H}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide~{N}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{H}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303