6S74: Crystal structure of CARM1 in complex with inhibitor UM305

PDB ID: 6S74Download
MMDB ID: 184873
PDB Deposition Date: 2019/7/4
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6S74: dimeric; determined by software (PISA)
Molecular Components in 6S74
Label Count Molecule
Proteins (2 molecules)
2
Histone-arginine Methyltransferase Carm1
(Gene symbol: CARM1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[[3-azanylpropyl-[3-(pyrimidin-2-ylamino)propyl]amino]methyl]oxolane-3,4-diol(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[[3-azanylpropyl-[3-(pyrimidin-2-ylamino)propyl]amino]methyl]oxolane-3,4-diol
2
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303