6S6W: Crystal Structure of human ALDH1A3 in complex with 2,6-diphenylimidazo[1,2-a]pyridine (compound GA11) and NAD+

PDB ID: 6S6WDownload
MMDB ID: 186718
PDB Deposition Date: 2019/7/3
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 3.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6S6W: tetrameric; determined by author and by software (PISA)
Molecular Components in 6S6W
Label Count Molecule
Proteins (4 molecules)
4
Aldehyde Dehydrogenase Family 1 Member A3
(Gene symbol: ALDH1A3)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
GLYCEROLGLYCEROL
3
2
2,6-diphenylimidazo[1,2-a]pyridine2,6-diphenylimidazo[1,2-a]pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303