6S6J: Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor

PDB ID: 6S6JDownload
MMDB ID: 190360
PDB Deposition Date: 2019/7/3
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6S6J: dimeric; determined by author and by software (PISA)
Molecular Components in 6S6J
Label Count Molecule
Proteins (2 molecules)
2
Transcriptional Enhancer Factor Tef-4
(Gene symbol: TEAD2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
MYRISTIC ACIDMYRISTIC ACID
2
1
ethyl 1-(4-azanylbutyl)-3-(3,4-dichlorophenyl)pyrazole-4-carboxylateethyl 1-(4-azanylbutyl)-3-(3,4-dichlorophenyl)pyrazole-4-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303