6S69: Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor

PDB ID: 6S69Download
MMDB ID: 190358
PDB Deposition Date: 2019/7/2
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 6S69: monomeric; determined by author
Molecular Components in 6S69
Label Count Molecule
Protein (1 molecule)
1
Transcriptional Enhancer Factor Tef-4
(Gene symbol: TEAD2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MYRISTIC ACIDMYRISTIC ACID
2
1
3-[3-(3,4-dichlorophenyl)-4-(2-phenylethylcarbamoyl)pyrazol-1-yl]propanoic acid3-[3-(3,4-dichlorophenyl)-4-(2-phenylethylcarbamoyl)pyrazol-1-yl]propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303