6S60: Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor

PDB ID: 6S60Download
MMDB ID: 190352
PDB Deposition Date: 2019/7/2
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6S60: monomeric; determined by author
Molecular Components in 6S60
Label Count Molecule
Protein (1 molecule)
1
Transcriptional Enhancer Factor Tef-4
(Gene symbol: TEAD2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MYRISTIC ACIDMYRISTIC ACID
2
1
4-[3-(3,4-dichlorophenyl)-4-[(phenylmethyl)carbamoyl]pyrazol-1-yl]butanoic acid4-[3-(3,4-dichlorophenyl)-4-[(phenylmethyl)carbamoyl]pyrazol-1-yl]butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303