6S40: Fragment AZ-001 binding at the p53pT387/14-3-3 sigma interface and additional sites

PDB ID: 6S40Download
MMDB ID: 188995
PDB Deposition Date: 2019/6/26
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6S40: tetrameric; determined by author and by software (PISA)
Molecular Components in 6S40
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
P53pt387
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
8
MAGNESIUM IONMAGNESIUM ION
2
8
4-chloranyl-1-benzothiophene-2-carboximidamide4-chloranyl-1-benzothiophene-2-carboximidamide
3
2
GLYCEROLGLYCEROL
4
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303