6S11: Crystal Structure of DYRK1A with small molecule inhibitor

PDB ID: 6S11Download
MMDB ID: 176884
PDB Deposition Date: 2019/6/18
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 2.445  Å
Source Organism:
Similar Structures:
Biological Unit for 6S11: monomeric; determined by author
Molecular Components in 6S11
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303