6RXC: Leishmania major pteridine reductase 1 (LmPTR1) in complex with inhibitor 4 (NMT-C0026)

PDB ID: 6RXCDownload
MMDB ID: 190040
PDB Deposition Date: 2019/6/7
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6RXC: tetrameric; determined by author and by software (PISA)
Molecular Components in 6RXC
Label Count Molecule
Proteins (4 molecules)
2
Pteridine Reductase 1
(Gene symbol: PTR1)
Molecule annotation
2
Pteridine Reductase 1
(Gene symbol: PTR1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
4
methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylatemethyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303