6RV3: Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493

PDB ID: 6RV3Download
MMDB ID: 178343
PDB Deposition Date: 2019/5/30
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6RV3: dimeric; determined by author and by software (PISA)
Molecular Components in 6RV3
Label Count Molecule
Proteins (2 molecules)
2
Potassium Channel Subfamily K Member 3
(Gene symbol: KCNK3)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
POTASSIUM IONPOTASSIUM ION
2
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
3
2
DECYL-BETA-D-MALTOPYRANOSIDEDECYL-BETA-D-MALTOPYRANOSIDE
4
1
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
5
1
[4-[[2-(4-bromophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-(2-fluorophenyl)methanone[4-[[2-(4-bromophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-(2-fluorophenyl)methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303