6RUQ: Structure of GluA2cryst in complex the antagonist ZK200775 and the negative allosteric modulator GYKI53655 at 4.65 A resolution

PDB ID: 6RUQDownload
MMDB ID: 189220
PDB Deposition Date: 2019/5/28
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 4.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6RUQ: tetrameric; determined by author and by software (PISA)
Molecular Components in 6RUQ
Label Count Molecule
Proteins (4 molecules)
4
Glutamate Receptor 2
(Gene symbol: Gria2)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
3
4
(8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide(8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide
4
4
{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303