6RUA: Structure of recombinant human butyrylcholinesterase in complex with a coumarin-based fluorescent probe linked to sulfonamide type inhibitor

PDB ID: 6RUADownload
MMDB ID: 183346
PDB Deposition Date: 2019/5/27
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 6RUA: trimeric; determined by author
Molecular Components in 6RUA
Label Count Molecule
Proteins (3 molecules)
3
Cholinesterase
(Gene symbol: BCHE)
Molecule annotation
Chemicals and Non-standard biopolymers (66 molecules)
1
32
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-L-fucopyranosealpha-L-fucopyranose
3
6
beta-L-fucopyranosebeta-L-fucopyranose
4
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
8
CHLORIDE IONCHLORIDE ION
6
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
7
2
diethyl-[6-[[2-[2-[2-[naphthalen-2-ylsulfonyl-[[(3~{R})-1-(phenylmethyl)piperidin-3-yl]methyl]amino]ethoxy]ethoxy]ethylamino]-oxidanyl-methyl]-7-oxidanylidene-1,3,4,4~{a},5,6,8,8~{a}-octahydronaphthalen-2-ylidene]azaniumdiethyl-[6-[[2-[2-[2-[naphthalen-2-ylsulfonyl-[[(3~{R})-1-(phenylmethyl)piperidin-3-yl]methyl]amino]ethoxy]ethoxy]ethylamino]-oxidanyl-methyl]-7-oxidanylidene-1,3,4,4~{a},5,6,8,8~{a}-octahydronaphthalen-2-ylidene]azanium
8
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303