6RST: TBK1 in complex with inhibitor compound 24

PDB ID: 6RSTDownload
MMDB ID: 182757
PDB Deposition Date: 2019/5/22
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 3.29  Å
Source Organism:
Similar Structures:
Biological Unit for 6RST: dimeric; determined by author
Molecular Components in 6RST
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase Tbk1
(Gene symbol: TBK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-[4-[(1~{R})-1-[2-[[5-[1-(cyclopropylmethyl)pyrazol-4-yl]-1~{H}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-tris(fluoranyl)propan-1-one1-[4-[(1~{R})-1-[2-[[5-[1-(cyclopropylmethyl)pyrazol-4-yl]-1~{H}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-tris(fluoranyl)propan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303