6RKM: Fragment AZ-022 binding at the p53pT387/14-3-3 sigma interface

PDB ID: 6RKMDownload
MMDB ID: 188981
PDB Deposition Date: 2019/4/30
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.88  Å
Source Organism:
Similar Structures:
Biological Unit for 6RKM: tetrameric; determined by author and by software (PISA)
Molecular Components in 6RKM
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Cellular Tumor Antigen P53
(Gene symbol: TP53)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
2
GLYCEROLGLYCEROL
4
4
4-phenyl-5-phenylazanyl-thiophene-2-carboximidamide4-phenyl-5-phenylazanyl-thiophene-2-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303