6R8R: Structure of the Wnt deacylase Notum in complex with isoquinoline 45

PDB ID: 6R8RDownload
MMDB ID: 175232
PDB Deposition Date: 2019/4/2
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.27  Å
Source Organism:
Similar Structures:
Biological Unit for 6R8R: monomeric; determined by author
Molecular Components in 6R8R
Label Count Molecule
Protein (1 molecule)
1
Palmitoleoyl-protein Carboxylesterase Notum
(Gene symbol: NOTUM)
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
~{N}-isoquinolin-6-yl-2-(2-methylphenoxy)ethanamide~{N}-isoquinolin-6-yl-2-(2-methylphenoxy)ethanamide
3
8
SULFATE IONSULFATE ION
4
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303