6R7F: Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome

PDB ID: 6R7FDownload
MMDB ID: 178976
PDB Deposition Date: 2019/3/28
Updated in MMDB: 2019/10
Experimental Method:
electron microscopy
Resolution: 8.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6R7F: 14-meric; determined by author
Molecular Components in 6R7F
Label Count Molecule
Proteins (14 molecules)
1
Cop9 Signalosome Complex Subunit 1
(Gene symbol: GPS1)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 2
(Gene symbol: COPS2)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 3
(Gene symbol: COPS3)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 4
(Gene symbol: COPS4)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 5
(Gene symbol: COPS5)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 6
(Gene symbol: COPS6)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 8
(Gene symbol: COPS8)
Molecule annotation
1
Cop9 Signalosome Complex Subunit 7B
(Gene symbol: COPS7B)
Molecule annotation
1
VON Hippel-lindau Disease Tumor Suppressor
(Gene symbol: VHL)
Molecule annotation
1
Elongin-b
(Gene symbol: ELOB)
Molecule annotation
1
Elongin-c
(Gene symbol: ELOC)
Molecule annotation
1
Cullin-2
(Gene symbol: CUL2)
Molecule annotation
1
E3 Ubiquitin-protein Ligase Rbx1
Molecule annotation
1
Nedd8
(Gene symbol: NEDD8)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303