6R3S: CRYSTAL STRUCTURE OF CDK8-CycC IN COMPLEX WITH COMPOUND 1

PDB ID: 6R3SDownload
MMDB ID: 186103
PDB Deposition Date: 2019/3/21
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.19  Å
Source Organism:
Similar Structures:
Biological Unit for 6R3S: dimeric; determined by author and by software (PISA)
Molecular Components in 6R3S
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 8
(Gene symbol: CDK8)
Molecule annotation
1
Cyclin-c
(Gene symbol: CCNC)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
6-[5-chloranyl-4-[(1~{S})-1-oxidanylethyl]pyridin-3-yl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide6-[5-chloranyl-4-[(1~{S})-1-oxidanylethyl]pyridin-3-yl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303