6R2E: Crystal structure of the human thymidylate synthase (hTS) interface variant Q62R

PDB ID: 6R2EDownload
MMDB ID: 174249
PDB Deposition Date: 2019/3/16
Updated in MMDB: 2019/04
Experimental Method:
x-ray diffraction
Resolution: 2.55  Å
Source Organism:
Similar Structures:
Biological Unit for 6R2E: dimeric; determined by software (PISA)
Molecular Components in 6R2E
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
4
SULFATE IONSULFATE ION
2
2
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acidN-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
3
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303