NCBI
National Center for
Biotechnology Information
Search
6R2E:
Crystal structure of the human thymidylate synthase (hTS) interface variant Q62R
PDB ID:
6R2E
Download
MMDB ID:
174249
PDB Deposition Date:
2019/3/16
Updated in MMDB:
2019/04
Experimental Method:
x-ray diffraction
Resolution:
2.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6R2E: dimeric; determined by software (PISA)
Molecular Components in 6R2E
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Thymidylate Synthase
(Gene symbol:
TYMS
)
Chemicals and Non-standard biopolymers (9 molecules)
1
4
SULFATE ION
2
2
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
3
3
CHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303