6QYQ: Crystal structure of human thymidylate synthase (hTS) variant R175C

PDB ID: 6QYQDownload
MMDB ID: 174481
PDB Deposition Date: 2019/3/9
Updated in MMDB: 2019/04
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6QYQ: dimeric; determined by author and by software (PISA)
Molecular Components in 6QYQ
Label Count Molecule
Proteins (2 molecules)
1
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
1
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
SULFATE IONSULFATE ION
2
2
CHLORIDE IONCHLORIDE ION
3
1
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acidN-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303