6QXU: Human TNKS1 in complex with 6,8-Difluoro-2-[4-(1-hydroxy-1-methyl-ethyl)-phenyl]-3H-quinazolin-4-one

PDB ID: 6QXUDownload
MMDB ID: 178532
PDB Deposition Date: 2019/3/8
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6QXU: monomeric; determined by author and by software (PISA)
Molecular Components in 6QXU
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase Tankyrase-1
(Gene symbol: TNKS)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
2
1
6,8-bis(fluoranyl)-2-[4-(2-oxidanylpropan-2-yl)phenyl]-3~{H}-quinazolin-4-one6,8-bis(fluoranyl)-2-[4-(2-oxidanylpropan-2-yl)phenyl]-3~{H}-quinazolin-4-one
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303