6QVL: Human SHMT2 in complex with pemetrexed

PDB ID: 6QVLDownload
MMDB ID: 179184
PDB Deposition Date: 2019/3/3
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 2.28  Å
Source Organism:
Similar Structures:
Biological Unit for 6QVL: dimeric; determined by author and by software (PISA)
Molecular Components in 6QVL
Label Count Molecule
Proteins (2 molecules)
2
Serine Hydroxymethyltransferase, Mitochondrial
(Gene symbol: SHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
GLYCEROLGLYCEROL
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
CALCIUM IONCALCIUM ION
4
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
5
1
N-{4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acidN-{4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303