6QU2: Crystal structure of DYRK1A complexed with FC162 inhibitor

PDB ID: 6QU2Download
MMDB ID: 185331
PDB Deposition Date: 2019/2/26
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6QU2: monomeric; determined by author
Molecular Components in 6QU2
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
SULFATE IONSULFATE ION
2
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
8-cyclopropyl-2-pyridin-3-yl-[1,3]thiazolo[5,4-f]quinazolin-9-one8-cyclopropyl-2-pyridin-3-yl-[1,3]thiazolo[5,4-f]quinazolin-9-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303