6QTG: Crystal structure of human CDK8/CYCC in complex with BI-1347

PDB ID: 6QTGDownload
MMDB ID: 185328
PDB Deposition Date: 2019/2/25
Updated in MMDB: 2020/04
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6QTG: dimeric; determined by author and by software (PISA)
Molecular Components in 6QTG
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 8
(Gene symbol: CDK8)
Molecule annotation
1
Cyclin-c
(Gene symbol: CCNC)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-~{N},~{N}-dimethyl-ethanamide2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-~{N},~{N}-dimethyl-ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303