6QJ7: Difluorophenyl diacylhydrazides: Potent inhibitors of Serum- and Glucocorticoid-inducible Kinase 1 (SGK1)

PDB ID: 6QJ7Download
MMDB ID: 184114
PDB Deposition Date: 2019/1/23
Updated in MMDB: 2020/02
Experimental Method:
x-ray diffraction
Resolution: 1.69  Å
Source Organism:
Similar Structures:
Biological Unit for 6QJ7: dimeric; determined by author and by software (PISA)
Molecular Components in 6QJ7
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase Catalytic Subunit Alpha
(Gene symbol: PRKACA)
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol: PKIA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}'-[(2~{S})-2-[3,5-bis(fluoranyl)phenyl]-2-oxidanyl-ethanoyl]-2-ethyl-3-methyl-4-oxidanyl-benzohydrazide~{N}'-[(2~{S})-2-[3,5-bis(fluoranyl)phenyl]-2-oxidanyl-ethanoyl]-2-ethyl-3-methyl-4-oxidanyl-benzohydrazide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303