6QGK: Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound

PDB ID: 6QGKDownload
MMDB ID: 176188
PDB Deposition Date: 2019/1/11
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6QGK: monomeric; determined by author and by software (PISA)
Molecular Components in 6QGK
Label Count Molecule
Protein (1 molecule)
1
Apoptosis Regulator Bcl-2,bcl-2-like Protein 1,apoptosis Regulator Bcl-2,bcl-2-like Protein 1
(Gene symbol: BCL2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide
2
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303