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6QGJ:
Structure of human Bcl-2 in complex with fragment/ABT-263 hybrid
PDB ID:
6QGJ
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MMDB ID:
176187
PDB Deposition Date:
2019/1/11
Updated in MMDB:
2019/09
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6QGJ: monomeric; determined by author and by software (PISA)
Molecular Components in 6QGJ
Label
Count
Molecule
Protein (1 molecule)
A
1
Apoptosis Regulator Bcl-2,bcl-2-like Protein 1,apoptosis Regulator Bcl-2,bcl-2-like Protein 1
(Gene symbol:
BCL2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[4-[(1~{R})-1-(6-methoxy-1,3-benzodioxol-5-yl)-2-pyrrolidin-1-yl-ethyl]phenyl]-~{N}-[4-[[(2~{R})-4-morpholin-4-yl-1-phenylsulfanyl-butan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonyl-benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303