6QEF: CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR (S)-3-Hydroxy-2-oxo-1-phenyl-pyrrolidine-3-carboxylic acid 3-chloro-5-fluoro-benzylamide

PDB ID: 6QEFDownload
MMDB ID: 174965
PDB Deposition Date: 2019/1/7
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 1.79  Å
Source Organism:
Similar Structures:
Biological Unit for 6QEF: monomeric; determined by author and by software (PISA)
Molecular Components in 6QEF
Label Count Molecule
Protein (1 molecule)
1
Methionine Aminopeptidase 2
(Gene symbol: METAP2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
GLYCEROLGLYCEROL
3
1
(3~{S})-~{N}-[(3-chloranyl-5-fluoranyl-phenyl)methyl]-3-oxidanyl-2-oxidanylidene-1-phenyl-pyrrolidine-3-carboxamide(3~{S})-~{N}-[(3-chloranyl-5-fluoranyl-phenyl)methyl]-3-oxidanyl-2-oxidanylidene-1-phenyl-pyrrolidine-3-carboxamide
4
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303