6QDH: Leishmania major N-myristoyltransferase in complex with quinazoline inhibitor IMP-0000906

PDB ID: 6QDHDownload
MMDB ID: 187224
PDB Deposition Date: 2019/1/1
Updated in MMDB: 2020/05
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 6QDH: monomeric; determined by author and by software (PISA)
Molecular Components in 6QDH
Label Count Molecule
Protein (1 molecule)
1
Glycylpeptide N-tetradecanoyltransferase
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
TETRADECANOYL-COATETRADECANOYL-COA
2
1
4-[ethyl(methyl)amino]-2-[methyl-(1-methylpiperidin-4-yl)amino]-~{N}-(1,3,5-trimethylpyrazol-4-yl)quinazoline-6-sulfonamide4-[ethyl(methyl)amino]-2-[methyl-(1-methylpiperidin-4-yl)amino]-~{N}-(1,3,5-trimethylpyrazol-4-yl)quinazoline-6-sulfonamide
3
1
~{N}-(1,3,5-trimethylpyrazol-4-yl)methanesulfonamide~{N}-(1,3,5-trimethylpyrazol-4-yl)methanesulfonamide
4
1
~{N}4-ethyl-~{N}2,~{N}4-dimethyl-~{N}2-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine~{N}4-ethyl-~{N}2,~{N}4-dimethyl-~{N}2-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
5
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303