6QB4: Mcl1-scFv complex with an indole acid inhibitor

PDB ID: 6QB4Download
MMDB ID: 181095
PDB Deposition Date: 2018/12/20
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.38  Å
Source Organism:
Similar Structures:
Biological Unit for 6QB4: dimeric; determined by author and by software (PISA)
Molecular Components in 6QB4
Label Count Molecule
Proteins (2 molecules)
1
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
(Gene symbol: MCL1)
Molecule annotation
1
Scfv55
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[3-[[(1~{R})-1,2,3,4-tetrahydronaphthalen-1-yl]oxy]propyl]-7-(1,3,5-trimethylpyrazol-4-yl)-1~{H}-indole-2-carboxylic acid3-[3-[[(1~{R})-1,2,3,4-tetrahydronaphthalen-1-yl]oxy]propyl]-7-(1,3,5-trimethylpyrazol-4-yl)-1~{H}-indole-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303