6Q9W: X-ray structure of compound 15 bound to HdmX: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

PDB ID: 6Q9WDownload
MMDB ID: 175491
PDB Deposition Date: 2018/12/18
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 6Q9W: monomeric; determined by author
Molecular Components in 6Q9W
Label Count Molecule
Protein (1 molecule)
1
Protein Mdm4
(Gene symbol: MDM4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(4~{S})-4-(4-chlorophenyl)-5-[(1~{S})-1-(3-chlorophenyl)ethyl]-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one(4~{S})-4-(4-chlorophenyl)-5-[(1~{S})-1-(3-chlorophenyl)ethyl]-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one
2
1
SULFATE IONSULFATE ION
3
2
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303