6Q9S: HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 14 AT 2.4A: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

PDB ID: 6Q9SDownload
MMDB ID: 175489
PDB Deposition Date: 2018/12/18
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6Q9S: monomeric; determined by author
Molecular Components in 6Q9S
Label Count Molecule
Protein (1 molecule)
1
Protein Mdm4
(Gene symbol: MDM4)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
3-[[6-chloranyl-3-[3-[(1~{S})-1-(2,4-dichlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-1~{H}-indol-2-yl]carbonylamino]-4-[4-(2-oxidanylidene-1,3-oxazinan-3-yl)piperidin-1-yl]benzoic acid3-[[6-chloranyl-3-[3-[(1~{S})-1-(2,4-dichlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-1~{H}-indol-2-yl]carbonylamino]-4-[4-(2-oxidanylidene-1,3-oxazinan-3-yl)piperidin-1-yl]benzoic acid
2
4
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
3
1
SULFATE IONSULFATE ION
4
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303