6Q36: TEAD4(216-434) complexed with optimized peptide 9 and myristoate (covalently bound) at 2.01A resolution: Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence

PDB ID: 6Q36Download
MMDB ID: 177060
PDB Deposition Date: 2018/12/3
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6Q36: tetrameric; determined by author
Molecular Components in 6Q36
Label Count Molecule
Proteins (4 molecules)
2
Transcriptional Enhancer Factor Tef-3
Molecule annotation
2
Ace-pro-6cw-arg-leu-arg-lys-2jh-hyp-asp-ser-phe-aln-lys-glu-pro-nh2
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
MYRISTIC ACIDMYRISTIC ACID
2
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303