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6Q2W:
Crystal structure of human ROR gamma LBD in complex with a quinoline sulfonamide inverse agonist
PDB ID:
6Q2W
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MMDB ID:
175904
PDB Deposition Date:
2018/12/3
Updated in MMDB:
2019/06
Experimental Method:
x-ray diffraction
Resolution:
1.99 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6Q2W: monomeric; determined by author
Molecular Components in 6Q2W
Label
Count
Molecule
Protein (1 molecule)
A
1
Nuclear Receptor Ror-gamma
(Gene symbol:
RORC
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2~{S})-1-[2,4-bis(chloranyl)-3-[[4-imidazol-1-yl-2-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-~{N}-methyl-pyrrolidine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303