6Q2R: Cryo-EM structure of RET/GFRa2/NRTN extracellular complex in the tetrameric form

PDB ID: 6Q2RDownload
MMDB ID: 180131
PDB Deposition Date: 2019/8/8
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 4.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6Q2R: dodecameric; determined by author
Molecular Components in 6Q2R
Label Count Molecule
Proteins (12 molecules)
4
Neurturin
(Gene symbol: NRTN)
Molecule annotation
4
Gdnf Family Receptor Alpha-2
(Gene symbol: GFRA2)
Molecule annotation
4
Proto-oncogene Tyrosine-protein Kinase Receptor RET
(Gene symbol: RET)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
16
CALCIUM IONCALCIUM ION
2
24
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303