6Q2O: Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry

PDB ID: 6Q2ODownload
MMDB ID: 180130
PDB Deposition Date: 2019/8/8
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6Q2O: hexameric; determined by author
Molecular Components in 6Q2O
Label Count Molecule
Proteins (6 molecules)
2
Neurturin
(Gene symbol: NRTN)
Molecule annotation
2
Gdnf Family Receptor Alpha-2
(Gene symbol: GFRA2)
Molecule annotation
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET
(Gene symbol: RET)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
8
CALCIUM IONCALCIUM ION
2
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303