6PZP: Crystal structure of caspase-1 in complex with VX-765

PDB ID: 6PZPDownload
MMDB ID: 190796
PDB Deposition Date: 2019/8/1
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.94  Å
Source Organism:
Similar Structures:
Biological Unit for 6PZP: dimeric; determined by author and by software (PISA)
Molecular Components in 6PZP
Label Count Molecule
Proteins (2 molecules)
1
Caspase-1
(Gene symbol: CASP1)
Molecule annotation
1
Caspase-1
(Gene symbol: CASP1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamideN-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303