6PUY: Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ426 (compound 4d)

PDB ID: 6PUYDownload
MMDB ID: 184109
PDB Deposition Date: 2019/7/18
Updated in MMDB: 2024/03
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6PUY: dodecameric
Molecular Components in 6PUY
Label Count Molecule
Proteins (8 molecules)
8
Chimeric Sso7d and Hiv-1 Integrase
Molecule annotation
Nucleotides(4 molecules)
2
Viral DNA Non-transferred Strand
Molecule annotation
2
Viral DNA Transferred Strand
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
4
ZINC IONZINC ION
3
2
4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303