6PUU: Human TRPM2 bound to 8-Br-cADPR and calcium

PDB ID: 6PUUDownload
MMDB ID: 179851
PDB Deposition Date: 2019/7/18
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6PUU: tetrameric; determined by author
Molecular Components in 6PUU
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily M Member 2
(Gene symbol: TRPM2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
(2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide(2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide
2
4
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303