6PS3: XFEL beta2 AR structure by ligand exchange from Timolol to Carvedilol

PDB ID: 6PS3Download
MMDB ID: 181299
PDB Deposition Date: 2019/7/12
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6PS3: monomeric; determined by software (PISA)
Molecular Components in 6PS3
Label Count Molecule
Protein (1 molecule)
1
Fusion Protein of Beta-2 Adrenergic Receptor and T4 Lysozyme
(Gene symbol: ADRB2)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
(2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL(2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL
2
4
SULFATE IONSULFATE ION
3
1
CHOLESTEROLCHOLESTEROL
4
6
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
5
4
OLEIC ACIDOLEIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303