6POW: Structure of human endotheial nitric oxide synthase heme domain in complex with 7-(5-(Aminomethyl)pyridin-3-yl)-4-methylquinolin-2-amine

PDB ID: 6POWDownload
MMDB ID: 187010
PDB Deposition Date: 2019/7/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 6POW: dimeric; determined by author and by software (PISA)
Molecular Components in 6POW
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Endothelial
(Gene symbol: NOS3)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
3
7-[5-(aminomethyl)pyridin-3-yl]-4-methylquinolin-2-amine7-[5-(aminomethyl)pyridin-3-yl]-4-methylquinolin-2-amine
4
6
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
5
1
ZINC IONZINC ION
6
1
GLYCEROLGLYCEROL
7
2
CHLORIDE IONCHLORIDE ION
8
1
GADOLINIUM ATOMGADOLINIUM ATOM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303