6PO8: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-((4-(2-Amino-4-methylquinolin-7-yl)-2-(aminomethyl)phenoxy)methyl)benzonitrile

PDB ID: 6PO8Download
MMDB ID: 187002
PDB Deposition Date: 2019/7/3
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.898  Å
Source Organism:
Similar Structures:
Biological Unit for 6PO8: dimeric; determined by author and by software (PISA)
Molecular Components in 6PO8
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Brain
(Gene symbol: NOS1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
2
4-{[2-(aminomethyl)-4-(2-amino-4-methylquinolin-7-yl)phenoxy]methyl}benzonitrile4-{[2-(aminomethyl)-4-(2-amino-4-methylquinolin-7-yl)phenoxy]methyl}benzonitrile
4
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303