6PM9: Crystal structure of the core catalytic domain of human O-GlcNAcase bound to MK-8719

PDB ID: 6PM9Download
MMDB ID: 179621
PDB Deposition Date: 2019/7/1
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.86  Å
Source Organism:
Similar Structures:
Biological Unit for 6PM9: tetrameric; determined by author and by software (PISA)
Molecular Components in 6PM9
Label Count Molecule
Proteins (4 molecules)
2
O-glcnacase Tim-barrel Domain
(Gene symbol: OGA)
Molecule annotation
2
O-glcnacase Stalk Domain
(Gene symbol: OGA)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(ethylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol(3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(ethylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303