6PLG: Crystal structure of human PHGDH complexed with Compound 15

PDB ID: 6PLGDownload
MMDB ID: 177797
PDB Deposition Date: 2019/6/30
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 6PLG: dimeric; determined by author and by software (PISA)
Molecular Components in 6PLG
Label Count Molecule
Proteins (2 molecules)
2
D-3-phosphoglycerate Dehydrogenase
(Gene symbol: PHGDH)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
(2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid(2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid
2
1
D-MALATED-MALATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303