6PF1: Crystal structure of the p300 acetyltransferase domain with allosteric inhibitor CPI-090 and CoA

PDB ID: 6PF1Download
MMDB ID: 180715
PDB Deposition Date: 2019/6/21
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.32  Å
Source Organism:
Similar Structures:
Biological Unit for 6PF1: monomeric; determined by author and by software (PISA)
Molecular Components in 6PF1
Label Count Molecule
Protein (1 molecule)
1
Histone Acetyltransferase P300
(Gene symbol: EP300)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
COENZYME ACOENZYME A
2
1
3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-indole3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-indole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303