6PAY: Structure of HsICDH1:Mg(II):ICT:NADPH(50%) complex reveals structural basis for observation of half-sites reactivity

PDB ID: 6PAYDownload
MMDB ID: 179610
PDB Deposition Date: 2019/6/12
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.199  Å
Source Organism:
Similar Structures:
Biological Unit for 6PAY: dimeric; determined by author and by software (PISA)
Molecular Components in 6PAY
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol: IDH1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
ISOCITRIC ACIDISOCITRIC ACID
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
4
5
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303