6PAI: Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820

PDB ID: 6PAIDownload
MMDB ID: 179609
PDB Deposition Date: 2019
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6PAI: tetrameric; determined by author and by software (PISA)
Molecular Components in 6PAI
Label Count Molecule
Proteins (4 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Ddb1- and Cul4-associated Factor 15
(Gene symbol: DCAF15)
Molecule annotation
1
RNA-binding Protein 39
Molecule annotation
1
Det1- and Ddb1-associated Protein 1
(Gene symbol: DDA1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
2
1
3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303